Lipoprotein(a)

What it is

Lipoprotein(a), or Lp(a), is an LDL-like particle with an extra protein attached; how much you have is roughly 80-90% determined by the genes you were born with and tends to stay fairly steady across adulthood. Because it's largely genetic, guideline bodies generally suggest it's reasonable for adults to have it checked at least once, rather than repeatedly — and it's not usually included in a standard lipid panel. Elevated Lp(a) has been independently associated with cardiovascular risk, but it doesn't respond much to the everyday lifestyle changes that move other lipids, so it's best interpreted with a clinician alongside your full risk picture and family history.

Typical range

Reference ranges vary between laboratories, and what is normal for you depends on your own history. Your own lab’s range is the one printed on your report.

Worth asking your clinician

• Was my Lp(a) reported in mg/dL or nmol/L, and how should I read this number in that unit?
• Given my Lp(a) result and my family history, does anything change in how we look at my overall risk?
• Since Lp(a) is mostly inherited, is there any reason to recheck it, or is this a once-in-a-lifetime test for me?